Computational Biology

Distance Measures for Tumor Evolutionary Trees
We introduce distance metrics on tumor evolutionary trees to use for benchmmarking inference methods or clustering trees.
Zach DiNardo, Kiran Tomlinson, Anna Ritz, Layla Oesper
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Distance Measures for Tumor Evolutionary Trees
Parameter, Noise, and Tree Topology Effects in Tumor Phylogeny Inference
An extended journal version of our 2018 BIBM paper. We examine how aspects of sequencing data and patterns of tumor evolution affect phylogeny inference.
Kiran Tomlinson, Layla Oesper
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Parameter, Noise, and Tree Topology Effects in Tumor Phylogeny Inference
Examining Tumor Phylogeny Inference in Noisy Sequencing Data
We explore when and how well tumor evolutionary histories can be inferred from multi-sample bulk sequencing data.
Kiran Tomlinson, Layla Oesper
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Examining Tumor Phylogeny Inference in Noisy Sequencing Data